Timothy P Holsgrove
My research focuses on using multi-disciplinary approaches to understand the mechanisms of degeneration and injury in the musculoskeletal system, and the evaluation of novel treatments and therapies. I have extensive expertise in the design, development and application of test systems and protocols, with a specific focus on the biomechanics of the spine, and the mechanisms of degeneration and injury of the spine. This has included the development of systems to characterise spinal specimens in six degrees of freedom, and evaluate the efficacy of spinal devices. This work has been developed further to introduce whole-organ intervertebral disc culture models, to investigate the interaction of mechanical and biochemical environments of the intervertebral disc, and evaluate regenerative therapies for disc degeneration in ways that has not been previously possible.
My research on musculoskeletal injuries has included projects to understand the mechanisms of catastrophic neck injury in Rugby Union, facet capsule injury in road traffic accidents, the acute and sustained pain resulting from exposure to whole body vibration using an in-vivo rat model, and has included investigations into vibrations during cycling and how they may be minimised. In additional to research in the field of spine biomechanics, I work with the Hip unit at the Royal Devon and Exeter Hospital to complete projects relating to biomechanics, patient activity and outcome measures, surgical procedures, and patient pathways.
Abstracts this author is presenting: