Friday, 31st May 50th International Society for the Study of the Lumbar Spine Annual Meeting 2024

• Transcriptomic analysis of lumbar and caudal intervertebral discs reveals anatomical level-dependent differences in immune regulatory pathway - MinKyu (Mark) Kim
• Effects of Age on Immune Cell Modulated Annulus Fibrosus Repair in Mouse Intervertebral Disc Herniation Injury - James Iatridis
• A mechanically active nucleus-pulposus on-chip model to reveal the interplay between mechanical loading and disc degeneration. - Andrea Mainardi
• Lipid Nanoparticles as mRNA delivery platform for intervertebral disc regeneration - Aida Moreira
• Accumulation of activated TCRαβ⁺CD8⁺ and TCRVδ1⁺T-cells in vertebral bone marrow of Modic change 1 patients - Stefan Dudli
• MUSCLE LOCATION-SPECIFIC DEGENERATION DIFFERENCE BETWEEN THE CORE AND LIMB MUSCLES: TSC1mKO MICE MODEL. - Wing Moon Raymond Lam

• Pain-related patterns of multifidus fat infiltration are spatially distinct from age-related and BMI-related patterns of fat infiltration - Karim Khattab
• Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disability - Paul W Hodges
• Prediction of Symptomatic Intravertebral Vacuum Cleft Sign with Machine Learning Algorithms - Risk Factor findings and Muscle Variables Strategy - Joonghyun Ahn
• IMPROVEMENT IN LUMBAR MULTIFIDUS MUSCLE COMPOSITION AFTER A 12-WEEK EXERCISE INTERVENTION IN PATIENTS WITH CHRONIC LOW BACK PAIN: A RANDOMIZED CONTROLLED TRIAL - Brent Rosenstein
• DISC DEGENERATION AND PARASPINAL MUSCLES ON PREOPERATIVE CT AND MRI AND THEIR ASSOCIATION WITH REVISION SURGERY AFTER LUMBAR FUSION - Marco D. Burkhard
• POSTURAL CONTROL AND PHYSICAL ACTIVITY BEFORE AND AFTER SURGERY FOR LUMBAR SPINAL STENOSIS: PILOT STUDY - Oliver B Zielinski

• Candidate epigenetic polygenic risk score (E-PRS) to predict pain response following surgical intervention for lumbar spinal stenosis due to spine osteoarthritis - Y. Raja Rampersaud
• Prediction of Low Back Pain Improvement in Decompression Surgery for Lumbar Spinal Stenosis-Usefulness of the BS-POP - Kazuyuki Watanabe
• Does sarcopenia affect postoperative clinical outcomes in lumbar decompression surgery? - Yukitoshi Shimamura
• Clinical Factors Associated with Patient Satisfaction Following Decompression Surgery for Lumbar Spinal Stenosis - Junichi Yamada
• Establishment of a Nomogram for Assessing the Risk of Ambulatory Surgery Conversion to Extended Stay for Lumbar Decompression Patients. - Koki Tsuchiya
• OLDER PEOPLE'S EXPERIENCE RECOVERING FROM SURGERY TO TREAT NEUROGENIC CLAUDICATION. A QUALITATIVE STUDY TO INFORM REHABILITATION TO IMPROVE POST-OPERATIVE WALKING - Suzanne McIlroy

• Simulation of multimodal interventions using a comprehensive collaborative model of low back pain - Jacek Cholewicki
• THE INFLUENCE OF LUMBAR INTERVERTEBRAL DISC DEGENERATION ON LOW BACK PAIN IS MODIFIED BY GENETIC PROPENSITY TO PAIN - Frances Williams
• Chronic low back pain mechanistic phenotypes: association with clinical features - Conor ONeill
• Measurement properties of self-reported outcome measures for older people with non-specific low back pain: a systematic review - Arnold Wong
• TRAJECTORIES OF PROMIS PHYSICAL FUNCTION, PAIN INTERFERENCE, AND SPINE LEGACY MEASURES IN 24 MONTHS FOLLOWING LUMBAR SPINE SURGERY - Kristin R Archer
• Cost-effectiveness of Condoliase Injection versus Micro-endoscopic Discectomy: A multicenter study - Takuya Takahashi

• BACTERIAL AND AUTOIMMUNE ENDOTYPES OF MODIC TYPE 1 CHANGE PATIENTS HAVE DISTINCT BLOOD CYTOKINE PROFILES - Irina Heggli
• Sex-Specific Associations Between Schmorl Nodes, Modic Changes, and Osteoporosis in a Large Population-Based Study: the Wakayama Spine Study - Masatoshi Teraguchi
• Disruption of the cartilaginous endplate may be the root pathology underlying so-called Modic changes on lumbar spine MR images: an experimental study of rabbits - Ming Guan
•   DOES INTRAOPERATIVE CELL-SALVAGED AUTOLOGOUS BLOOD TRANSFUSION IN METASTATIC SPINE TUMOUR SURGERY IMPROVE LONG TERM CLINICAL OUTCOMES? A PROSPECTIVE CLINICAL STUDY - Satyanarayan Naresh Kumar
• Surgical outcome for spinal metastasis of renal cell carcinoma - Yoshiki Takeoka
• TOTAL EN BLOC SPONDYLECTOMY FOR PRIMAY MALIGNANT AND LOCALLY AGGRESSIVE INTERMEDIATE BONE TUMORS ARISING IN THE LOWER LUMBAR SPINE - Yoshihiro Matsumoto

• Development of intervertebral disc regenerative therapy using highly-purified mesenchymal stem cells and bioabsorbable alginate gel: Translational research using a large animal model - DAISUKE UKEBA
• Hydrogel-Based Delivery of Hypoxic Preconditioned Stem Cell-Derived Extracellular Vesicles Mitigates Senescence in Nucleus Pulposus Cells: Regulating Redox Homeostasis for Disc Degeneration Treatment - MING GUAN
• Off-the-shelf NP cell therapy for canine disc degeneration at different severity levels - Jordy Schol
• Injectable cell encapsulated hyaluronic acid microgels for nucleus pulposus regeneration  - Parisa torabi-rahvar
• The potential of nasal chondrocyte spheroids for intervertebral disc repair - Raphael Schmid
• A PRO-DEGENERATIVE ENVIRONMENT PROMOTES THE REGENERATIVE POTENTIAL OF EXTRACELLULAR VESICLES DERIVED FROM NOTOCHORDAL CELLS - Daniele Corraini

• The Role of Paraspinal Muscles in Degenerative Spondylolisthesis L4/L5: A Cross-Sectional Study in 138 Patients Undergoing Surgery - Paul C Köhli
• EVALUATION OF "APPROPRIATE USE CRITERIA" FOR SURGICAL DECISION MAKING IN LUMBAR DEGENERATIVE SPONDYLOLISTHESIS. A CONTROLLED, MULTICENTRE, PROSPECTIVE OBSERVATIONAL STUDY - Francine Mariaux
• Does facet joint angulation difference pre-exist or result from remodeling in degenerative spondylolisthesis? A radiological study in double-level versus single-level degenerative spondylolisthesis - Xu Sun
• Risk factors of postoperative ileus in corrective spinal surgery: The analysis of the retrocrural space - SHUHEI OHYAMA
• Validation study of MR bone like image for staging lumbar spondylolysis in children - Yutaka Kinoshita
• A Focus on Intervertebral Disc Injury in the Correction Loss of Percutaneous Pedicle Screw Fixation for High Energy Traumatic Thoracolumbar Spine Injury - Shinichi Ishihara

• MODIC CHANGE BONE MARROW NEUTROPHILS ARE ACTIVATED AND ACTIVATED NEUTROPHILS DEGRADE CARTILAGE ENDPLATES - Irina Heggli
•  CUTIBACTERIUM ACNES IS PRESENT IN NON-HERNIATED HUMAN DISCS; ITS POSITIVITY RATE CORRELATES WITH THE PATIENT'S AGE - Andrea Nüesch
• Harnessing the Immunosuppressive Potential of Primed MSCs to Suppress Inflammation in Degenerating Intervertebral Discs - Nick Herger
• Annulus Fibrosus Injury Drives Acute Inflammation and Chronic Glial Activation in Dorsal Root Ganglion and Spinal Cord: An In-vivo Rat Discogenic Pain Model - James C Iatridis
• CHARACTERISTICS OF THE EXTRACELLULAR VESICLES FROM HUMAN INTERVERTEBRAL DISC CELLS - Lisbet Haglund

Best Abstract Paper and Poster prize presentations.

Closing remarks from new ISSLS President.